The answer for this is simple, the tool to manage ODBC entry's on Windows is ODBCAD32.exe
If you can't add an entry on the SYSTEM DSN tab the first thing you need to remember is that you have to run the tool with administrative provilidges to be able to add entrys in this tab. Otherwise the only tab you will have permissions to add entry's to will be the USER DSN.
This obviously is because the tool needs to change registry key's and the SYSTEM DSN is in the Machine Scope wether the USER DSN is in the USER scope.
To run the tool odbcad32 with admin privilidges without logging off that current user's account you can do the following at the command line:
C:\> runas /U:domain\adminuser odbcad32.exe
and enter password
Taken from: http://bitboard.blogspot.com/